Richard Nass, PhD

Associate Professor of Pharmacology and Toxicology
Principle Investigator, Center for Environmental Health
Principle Investigator, Stark Neurosciences Research Institute

635 Barnhill Drive
MS 549
Indianapolis, IN 46202
ricnass@iupui.edu
(317) 278-8505



  Labsite

 Center for Environmental Health

Stark Neurosciences Research Institute





Richard Nass

Research Interests

Molecular mechanisms involved in Parkinson's disease and dopamine neurodegeneration; identification of novel therapeutic targets and compounds that can protect against dopamine neuron degeneration.

 

Selected Publications:

Nass, R., Hahn, M., Jessen, T., McDonald, P., Carvelli, L., Blakely, RD (2005) A genetic screen in C. elegans for dopamine neuron insensitivity to 6-hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking. J. Neurochemistry 94:774-785

Nass, R., Nichols, CD. (2007) Invertebrates as powerful genetic models for human neurodegenerative diseases. In: Handbook of Contemporary Neuropharmacology, ed. David Sibley, Israel Hanin, and Michael Kuhar. John Wiley and Sons, 567-588

Jiang, GC-T., Tidwell, K., McLaughlin, B., Cai, J., Gupta, Milatovic, D., Nass, R., Aschner (2007) Neurotoxic potential of depleted uranium - effects in primary corticoal neuron cultures and in Caenorhabditis elegans. Toxicol Sci, 99:553-565

Nass, R., Hamza, I. (2007) The nematode C. elegans as a model to explore toxicology in vivo: solid and axenic growth culture conditions and compound exposure parameters, Curr Protocols Toxicology, 1.9.1-1.9.18

Nass, R. and Przedborski, S., "Parkinson's disease: pathogenic and therapeutic insights from toxin and genetic models," Reference Book, Elsevier Press. Expected release date: Spring 2008.