POSTDOCTORAL POSITION available to investigate the role of a DNA repair enzyme in drug resistance in the protozoan parasite Toxoplasma gondii. Related to the malaria parasite, Toxoplasma causes serious disease in immuno-compromised (AIDS) patients and during pregnancy. We have shown that disruption of a mitochondrial MutS homolog results in multi-drug resistance and that this protein is part of an inducible death pathway. Potential projects include molecular and biochemical analyses of mitochondrial function in the resistant mutant and characterization of signaling event in the MutS dependent death pathway. Position requires a Ph.D., expertise in biochemistry, molecular and cellular biology, and excellent communication skills (speaking and writing English). Experience in molecular parasitology, DNA damage, or mitochondrial function is a plus.
Submit cover letter, CV, and contact information for three references to Dr. Gustavo Arrizabalaga (email@example.com).
IU is an EEO/AA Employer, M/F/D.